COEXISTENCE OF TEMPI SYNDROME AND LEUKOCYTOCLASTIC VASCULITIS SUCCESSFULLY TREATED WITH AUTOLOGOUS STEM CELL TRANSPLANTATION

Coexistence of TEMPI syndrome and leukocytoclastic vasculitis successfully treated with autologous stem cell transplantation

Abstract The TEMPI syndrome is a very rare paraneoplastic syndrome associated with plasma cell dyscrasia and monoclonal gammopathy.First described in 2011, the pathophysiology of TEMPI syndrome is still unknown.Essential for diagnosis is to recognize the five Stairarm Repair Kit clinical findings: telangiectasias, erythrocytosis and elevated serum

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Prediction of Friction Resistance for Slurry Pipe Jacking

Friction resistance usually constitutes one of the two main components for the calculation of required jacking force.This paper provides a new approach to predict the friction resistance of slurry pipe jacking.First, the existing prediction equations and their establishment VL Series Parts methods and essential hypotheses used were carefully summar

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Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies lacking effective therapies.KRAS mutations that occur in over 90% of PDAC are major oncogenic drivers of PDAC.The MAPK signaling pathway plays a central role in KRAS-driven oncogenic signaling.However, pharmacological inhibitors of the MAPK Microphone Acce

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